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Pathogenicity of Candida paratropicalis.
Archives of Pathology & Laboratory Medicine
|November 1, 1983
Summary
A new yeast, Candida paratropicalis, causes serious infections despite in vitro drug sensitivity. This review details clinical cases to understand its relevance in human health.
Area of Science:
- Medical Mycology
- Infectious Diseases
Background:
- Candida paratropicalis is a recently described yeast species.
- Understanding the clinical significance of emerging fungal pathogens is crucial.
Observation:
- Review of nine cases of Candida paratropicalis infections.
- Isolates were recovered from various body sites, including blood.
- In vitro susceptibility testing showed sensitivity to amphotericin B and fluconazole.
Findings:
- Despite in vitro drug sensitivity, infections caused significant morbidity and mortality.
- Candida paratropicalis demonstrates clinical relevance as a human pathogen.
Implications:
- Highlights the need for vigilance regarding new Candida species.
- Suggests potential challenges in treating infections caused by this emerging yeast.