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Related Experiment Videos

Study on the dissolution behaviour of calcium fluoride.

C Bruun, D Moe, H E Madsen

    Scandinavian Journal of Dental Research
    |August 1, 1983
    PubMed
    Summary

    Calcium fluoride dissolution is extremely slow, persisting for weeks and influenced by crystal size. This slow release suggests topical fluoride applications may offer long-term benefits for dental caries.

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    Area of Science:

    • Materials Science
    • Analytical Chemistry
    • Dental Research

    Background:

    • Calcium fluoride (CaF2) is a key compound in topical fluoride treatments for preventing dental caries.
    • Understanding the dissolution kinetics of CaF2 is crucial for assessing the longevity and efficacy of fluoride applications.

    Purpose of the Study:

    • To investigate the dissolution rate and behavior of analytical calcium fluoride preparations in aqueous solutions.
    • To correlate dissolution characteristics with crystal size and experimental conditions.

    Main Methods:

    • Dissolution studies in aqueous solution.
    • Analysis of dissolved calcium (Ca) and fluoride (F) ions.
    • X-ray diffractometry of original and partially dissolved samples compared to natural fluorite.

    Main Results:

    • Calcium fluoride dissolution is exceptionally slow, reaching a near-equilibrium state within 1-15 weeks, far below saturation.
    • Dissolution rate is directly related to crystal size, with finer fractions dissolving faster.
    • Partial dissolution led to an increase in mean crystal size, indicating the loss of smaller crystals.
    • Using a dialysis bag significantly reduced the dissolution rate and increased the undissolved fraction.

    Conclusions:

    • The extremely slow dissolution of calcium fluoride supports its persistence in dental tissues.
    • Accumulated calcium fluoride in early carious lesions may remain for extended periods, contributing to caries resistance.
    • Findings have implications for optimizing topical fluoride therapies for long-term caries prevention.

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