CT follow-up of hepatic and splenic fungal microabscesses

Three patients with acute myelogenous leukemia underwent abdominal computed tomographic (CT) examination for recent deterioration in clinical status. The diagnosis of hepatic and splenic microabscesses was correctly suggested in each patient on the basis of this study. In addition, CT accurately assessed the efficacy of antifungal therapy on follow-up studies. In this limited series of patients, CT was superior to clinical and laboratory evaluation in predicting the degree of parenchymal infection in the liver and spleen during treatment, confirmed by histologic specimens.