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The trilateral retinoblastoma syndrome
Transactions of the Ophthalmological Societies of the United Kingdom
|January 1, 1983
Summary
Bilateral retinoblastoma can occur with intracranial tumors, likely from ectopic foci, not metastasis. CT scans are recommended for all bilateral retinoblastoma cases.
Area of Science:
- Ophthalmology
- Pediatric Oncology
- Neurology
Background:
- Bilateral retinoblastoma is a rare pediatric eye cancer.
- Intracranial involvement in retinoblastoma is uncommon and its origin debated.
Observation:
- Two cases of bilateral retinoblastoma with intracranial tumors are presented.
- Tumors were located in the pineal region in one case and the suprasellar region in the other.
Findings:
- The intracranial tumors are believed to be ectopic foci of retinoblastoma.
- This suggests a developmental origin rather than metastatic spread.
Implications:
- Computed tomography (CT) scanning should be considered in the routine assessment of bilateral retinoblastoma.
- Early detection of intracranial involvement can guide treatment strategies.