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Updated: Aug 13, 2026
11:15
In Situ Detection of Bacteria within Paraffin-embedded Tissues Using a Digoxin-labeled DNA Probe Targeting 16S rRNA
Published on: May 21, 2015
[Anaerobic microbes in perimandibular inflammation]
Revue De Stomatologie Et De Chirurgie Maxillo-Faciale
|January 1, 1984
Summary
Perimandibular inflammation is often caused by anaerobic Gram-negative bacteria. Dental bacterial flora showed the highest sensitivity to davercin among six tested antibiotics.
Area of Science:
- Oral microbiology
- Infectious diseases
- Pharmacology
Background:
- Perimandibular inflammation presents a complex clinical challenge.
- Understanding the causative bacterial agents and their antibiotic susceptibility is crucial for effective treatment.
Purpose of the Study:
- To identify the bacterial flora associated with perimandibular inflammation.
- To determine the antibiotic resistance patterns of these bacteria.
- To evaluate the efficacy of specific antibiotics, including davercin.
Main Methods:
- Bacteriological examinations were performed on 16 patients with perimandibular inflammation.
- Isolated bacterial strains (73 total: 47 anaerobic, 26 aerobic) were tested for resistance to six antibiotics: davercin, erythromycin, penicillin, ampicillin, tetracycline, and chloramphenicol.
- Gram staining differentiated bacterial strains (47 Gram-negative, 26 Gram-positive).
Main Results:
- Anaerobic Gram-negative bacteria were identified as the primary cause of perimandibular inflammatory lesions.
- Streptococcus viridans was found more frequently in patients than in healthy individuals.
- Bacterial flora of dental origin demonstrated greater sensitivity to davercin compared to the other five antibiotics tested.
Conclusions:
- Anaerobic Gram-negative bacteria are key pathogens in perimandibular inflammation.
- Davercin exhibits promising efficacy against the prevalent bacterial flora in dental infections.
- Targeted antibiotic therapy, potentially involving davercin, may improve treatment outcomes for perimandibular inflammation.
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