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Updated: Aug 19, 2026

A Preclinical Mouse Model of Osteosarcoma to Define the Extracellular Vesicle-mediated Communication Between Tumor and Mesenchymal Stem Cells
Published on: May 6, 2018
[Scanning electron microscopy and elementary analytic studies of osteosarcoma]
Abstract:
By scanning electron microscopical (SEM) screening analyses of 14 osteosarcomas characteristic three-dimensional structures of tumor osteoid could be demonstrated. These osteoid formations are highly characteristic for osteosarcoma; we did not find them at any other bone tumor or tumor like lesion until now. With these results a better understanding of characteristic growth patterns of bone tumors could be achieved by SEM. No specific results could be found by elementar analysis, x-ray microanalysis, x-ray fluorescence and x-ray diffractometer techniques. The significance of single interesting values has to be evaluated in the future.
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