[Blood platelet function following gamma globulin infusions in children with acute lymphatic leukemia during the remission-maintaining long-term therapy]
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Platelet function tests prior to and post intravenous gammaglobulin infusions (i.v. IgG) were performed in 20 children with acute lymphoblastic leukemia under conventional maintainance therapy. Platelet function was not influenced in 8 patients with decreased preinfusion IgG-levels. Severe platelet function defects, resembling an acquired storage pool disease, post i.v. IgG-infusion, however, were observed in 2 of 12 patients with normal preinfusion IgG-levels.
Platelet function tests prior to and post intravenous gammaglobulin infusions (i.v. IgG) were performed in 20 children with acute lymphoblastic leukemia under conventional maintainance therapy. Platelet function was not influenced in 8 patients with decreased preinfusion IgG-levels. Severe platelet function defects, resembling an acquired storage pool disease, post i.v. IgG-infusion, however, were observed in 2 of 12 patients with normal preinfusion IgG-levels.