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Interpretation of LOD scores with a set of marker loci
Genetic Epidemiology
|January 1, 1984
Abstract:
The problem discussed is that of interpreting LOD scores when multiple markers are tested for linkage with a particular disease locus. Provided the tests are based on independent segregations, both the maximum and the average LOD can be translated into a score that would have the same significance level were it the result of a single test.