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Related Experiment Videos

Hyperparathyroidism in the elderly.

S Tibblin, N Pålsson, J Rydberg

    Annals of Surgery
    |February 1, 1983
    PubMed
    Summary

    Primary hyperparathyroidism is common in the elderly, affecting 1.5% of those studied. Surgical treatment is effective, with most patients experiencing symptom relief and normalized calcium levels post-operation.

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    Area of Science:

    • Endocrinology
    • Geriatric Medicine
    • Surgical Oncology

    Background:

    • Primary hyperparathyroidism (PHPT) is a significant endocrine disorder.
    • Its prevalence and clinical manifestations in geriatric populations require further investigation.

    Purpose of the Study:

    • To determine the prevalence of PHPT in a geriatric cohort.
    • To evaluate the clinical presentation, surgical outcomes, and therapeutic efficacy of PHPT treatment in elderly patients.

    Main Methods:

    • A prospective study of 1129 geriatric individuals over three months.
    • Retrospective analysis of 158 elderly patients (age > 64) who underwent surgery for PHPT over ten years.
    • Preoperative assessment of symptoms and postoperative biochemical and clinical follow-up.

    Main Results:

    • PHPT prevalence was 1.5% in the geriatric population.
    • Common preoperative symptoms included neuromuscular issues (80%), renal insufficiency (16%), kidney stones (16%), and gastrointestinal problems (38%).
    • Solitary adenomas accounted for 80% of cases; 94% achieved normocalcemia post-surgery with good/fair symptom improvement.

    Conclusions:

    • PHPT is highly prevalent in the elderly and presents with diverse symptoms.
    • Surgical intervention for PHPT in the elderly is safe and effective, leading to significant symptom resolution and biochemical normalization with low morbidity.

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