Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Metronidazole.

J E Rosenblatt, R S Edson

    Mayo Clinic Proceedings
    |March 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Metronidazole is a versatile antimicrobial effective against anaerobic bacteria and parasites like those causing trichomoniasis, amebiasis, and giardiasis. It

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Donor-transmitted toxoplasmosis in liver transplant recipients: a case report and literature review.

    Transplant infectious disease : an official journal of the Transplantation Society·2007
    Same author

    Real-time PCR in clinical microbiology: applications for routine laboratory testing.

    Clinical microbiology reviews·2006
    Same author

    Comparison of the Roche LightCycler vanA/vanB detection assay and culture for detection of vancomycin-resistant enterococci from perianal swabs.

    Journal of clinical microbiology·2004
    Same author

    Real-time PCR method for detection of Encephalitozoon intestinalis from stool specimens.

    Journal of clinical microbiology·2002
    Same author

    Multilaboratory comparison of growth characteristics for anaerobes, using 5 different agar media.

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2002
    Same author

    Multilaboratory comparison of anaerobe susceptibility results using 3 different agar media.

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2002
    Same journal

    Advancing Pulmonary Fibrosis Care: Integrating Genomic Insights Into Clinical Practice.

    Mayo Clinic proceedings·2026
    Same journal

    RAAS Inhibition in the ICU: Stop, Continue, or Restart?

    Mayo Clinic proceedings·2026
    Same journal

    Chronic Kidney Disease-In the Limelight, July 2026.

    Mayo Clinic proceedings·2026
    Same journal

    In Reply: Long-Term Cardiovascular Burden After Carotid Endarterectomy: Moving Beyond Conventional Risk Profiling.

    Mayo Clinic proceedings·2026
    Same journal

    Long-Term Cardiovascular Burden After Carotid Endarterectomy: Moving Beyond Conventional Risk Profiling.

    Mayo Clinic proceedings·2026
    Same journal

    Real-World Comparative Effectiveness of Tirzepatide and Semaglutide for Obesity: A Multicentered Study.

    Mayo Clinic proceedings·2026
    See all related articles

    Area of Science:

    • Pharmacology and Microbiology
    • Antimicrobial Agents
    • Infectious Diseases

    Background:

    • Metronidazole, a nitroimidazole derivative, exhibits unique antimicrobial properties.
    • Its activity is primarily against anaerobic bacterial and parasitic organisms.
    • Established efficacy in treating trichomoniasis, amebiasis, and giardiasis.

    Purpose of the Study:

    • To review the role and efficacy of metronidazole in treating anaerobic infections.
    • To highlight its application in surgical prophylaxis and specific gynecological conditions.

    Main Methods:

    • Review of clinical studies and established therapeutic guidelines.
    • Analysis of metronidazole's spectrum of activity against anaerobic pathogens.
    • Evaluation of pharmacokinetic and safety profiles.

    Related Experiment Videos

    Main Results:

    • Metronidazole is highly effective against most anaerobes, including the Bacteroides fragilis group.
    • Demonstrated efficacy in prophylaxis for colorectal surgery and treatment of abdominal sepsis.
    • Considered the treatment of choice for nonspecific vaginitis caused by anaerobes and Gardnerella vaginalis.

    Conclusions:

    • Metronidazole is a principal agent for treating anaerobic bacterial infections.
    • It offers a favorable safety profile with infrequent and minimal side effects.
    • Achieves adequate blood concentrations via oral and intravenous administration.