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Chancroid in Nigeria.

R M Joshi, R V Lawande

    Transactions of the Royal Society of Tropical Medicine and Hygiene
    |January 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Chancroid, a bacterial infection, affected 4.38% of patients at a Nigerian hospital. Most cases were confirmed by direct smear, and all patients successfully responded to antibiotic treatment.

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    Area of Science:

    • Infectious Diseases
    • Bacteriology
    • Public Health

    Background:

    • Chancroid is a sexually transmitted infection caused by Haemophilus ducreyi.
    • Accurate incidence data is crucial for understanding disease burden and guiding public health interventions.

    Purpose of the Study:

    • To determine the incidence of chancroid among patients attending a Special Treatment Clinic in northern Nigeria.
    • To evaluate diagnostic methods and treatment efficacy for chancroid.

    Main Methods:

    • Retrospective analysis of patient records from February to August 1982.
    • Diagnosis based on clinical presentation and laboratory confirmation (direct smear, bacterial culture).
    • Treatment outcomes assessed based on patient response to antibiotics.

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    Main Results:

    • Out of 776 patients, 34 (4.38%) were diagnosed with chancroid.
    • Direct smear for Haemophilus ducreyi was positive in 33 cases; one case showed probable L-forms.
    • Bacterial culture confirmed H. ducreyi in only three cases.
    • All patients showed a positive response to co-trimoxazole and tetracycline treatment.

    Conclusions:

    • Chancroid represents a significant public health concern in northern Nigeria, with a notable incidence rate.
    • Direct smear microscopy is a valuable diagnostic tool for chancroid, offering higher sensitivity than culture in this study.
    • Co-trimoxazole and tetracyclines are effective treatments for chancroid.