[Recovery from chronic polyradiculoneuritis after high-dose intravenous corticoid therapy]

Area of Science:

• Neurology
• Immunology

Background:

• Chronic relapsing polyneuropathy (CRPN) is an inflammatory neurological disorder.
• Oral prednisone is a common but sometimes ineffective treatment for CRPN.

Observation:

• A patient with CRPN refractory to oral prednisone therapy was identified.
• The patient had a 7-year history of the condition without improvement.

Findings:

• Three intravenous infusions of 1.5 g methylprednisolone were administered.
• Complete recovery from CRPN was achieved following the treatment.

Implications:

• Intravenous methylprednisolone may be a highly effective treatment for prednisone-resistant CRPN.
• Sustained recovery suggests a potential long-term therapeutic benefit for this challenging condition.