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Related Experiment Videos

Doxepin and tinnitus.

R N Golden, D L Evans, C H Nau

    Southern Medical Journal
    |September 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Tinnitus, a ringing in the ears, can be a side effect of the antidepressant doxepin. This case study shows how stopping and restarting doxepin can cause tinnitus to appear and disappear.

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    Area of Science:

    • Otolaryngology
    • Pharmacology

    Background:

    • Tinnitus is a common auditory symptom.
    • Doxepin is a tricyclic antidepressant used for depression and anxiety.

    Observation:

    • A 66-year-old female patient experienced tinnitus.
    • The tinnitus occurred during treatment with a standard dose of doxepin.

    Findings:

    • Discontinuation of doxepin led to the resolution of tinnitus.
    • Reintroduction of doxepin resulted in the recurrence of tinnitus, confirming a causal link.

    Implications:

    • This case highlights the potential ototoxic effects of doxepin.
    • Clinicians should consider drug-induced tinnitus in patients on doxepin therapy.