Biorheological aspect in relation to endoendothelial fibrin lining

In connection with the findings of Copley et al. on the reduction of the apparent viscosity of blood, plasma and serum in contact with fibrin, a theoretical analysis of a Newtonian flow through a fibrin-coated tube was developed, taking into account the electric double layer between the fibrin layer and blood. the Gouy-Chapman model for the diffuse double layer was introduced instead of the Helmholtz model. It is shown that the reduction of the apparent viscosity is governed by an "electric double layer parameter" a, which is proportional to the term sigma'zeta/R. zeta is the zeta potential, R is the radius of the tube, and sigma' is the positive surface charge density corresponding to the fixed negative density on the fibrin layer.