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Heterotopic interhemispheric cortical connections in the rat

In the rat, contrary to other species, interhemispheric cortical connections have been considered to travel largely between homotopical regions only. Based on iontophoretic injections of horseradish peroxidase, the present study reports extensive heterotopic interhemispheric connections between posterior insular (perirhinal) regions of the lateral part of the hemisphere and anterior prefrontal regions of the medial hemisphere and vice versa. Generally, the areas connected interhemispherically are also connected intrahemispherically. The ratio of contralateral projections appears to be less than one third of the ipsilateral ones.

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