Ordered synthesis and degradation of liver glycogen involving 2-amino-2-deoxy-D-glucose

The incorporation of 2-amino-2-deoxy-D-glucose from precursor 2-amino-2-deoxy-D-galactose into liver glycogen has been shown to be a metabolically inhomogeneous process after starvation. The protein-to-polysaccharide ratio is also heterogeneous with respect to molecular size, and enhanced overall as compared to normal glycogen. The results are discussed from the viewpoint of a molecular order in the synthesis and degradation of liver glycogen.