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Related Experiment Videos

[Hemochemical data in the function study of the senile kidney].

A E Tàmmaro, O Bonaccorso, P Gemmellaro

    Minerva Medica
    |April 14, 1978
    PubMed
    Summary

    Serum creatinine (SC) levels are higher in older males and increase with age. Serum creatinine is a more reliable indicator of kidney filtration rate than endogenous creatinine clearance in adults over 60.

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    Journal of the American Geriatrics Society·1994

    Area of Science:

    • Nephrology
    • Biochemistry
    • Gerontology

    Context:

    • Assessing renal function in aging populations is crucial.
    • Serum creatinine is a commonly used biomarker for kidney function.
    • Age and sex influence serum creatinine levels.

    Purpose:

    • To evaluate serum creatinine (SC) values in healthy adults over 60.
    • To compare the reliability of SC and endogenous creatinine clearance (ECC) as indicators of glomerular filtration rate (GFR).

    Summary:

    • A survey of 2426 individuals over 60, free of kidney disease, revealed higher SC values in males and an age-related increase.
    • Correlation analysis indicated that SC is a more dependable marker for GFR than ECC in this demographic.
    • Findings suggest SC is a superior index for assessing kidney function in the elderly.

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    Impact:

    • Provides evidence for age and sex-specific reference ranges for serum creatinine.
    • Recommends serum creatinine as a more accurate measure of GFR in older adults.
    • Informs clinical practice regarding kidney function assessment in geriatrics.