Development of carpal bone cysts as revealed by radiography

In 11 patients with carpal bone cysts the course of the intraosseous lytic lesion could be followed over periods from 2 to 27 years. The cysts were found to develop from an area of sparse trabeculae of reduced mineral content to a well-defined cavity, in some instances surrounded by a sclerotic zone. In 2 instances the lytic process caused progressive destruction of the subchondral layers of the affected bone resulting in communication with the adjacent joint space. The findings support the theory that carpal bone cysts are intraosseous lesions probably caused by vascular disturbances from mechanical stress and repeated trauma. The term intraosseous ganglion is a misnomer and should be avoided.