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Updated: Sep 11, 2026

Implementation of In Vitro Drug Resistance Assays: Maximizing the Potential for Uncovering Clinically Relevant Resistance Mechanisms
Published on: December 9, 2015
A systemic approach to resistance: theoretical and technical considerations
Abstract:
A systemic approach to resistance allows the individual therapist to appreciate the adaptive, protective, systems-maintaining aspects of "help-rejecting" behaviors which might otherwise elicit negatively toned interventions that serve to heighten or rigidify a resistant impasse. This article illustrates how a systemic perspective assists the psychodynamically oriented psychotherapist in adopting a neutral and respectful attitude toward a patient's resistant posture, and also explores implications for the theoretical understanding and technical management of resistance.
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