Treatment of asthenozoospermia by intratesticular testosterone therapy

A single intratesticular injection of 0.5 cc of 50 mg/ml of an aqueous testosterone suspension was administered to 14 patients with asthenozoospermia. In 7 cases, injection was combined with ultrasound of 0.5 w/cm2 for 2 min weekly for 4 weeks. In another 4 cases, only ultrasound was applied. Intratesticular injection with or without ultrasound caused a significant increase of motility percentage. Sperm density improved in cases that were associated with oligozoospermia (less than 20 million/ml). Ultrasound therapy (0.5 w/cm2 for 2 min) used alone had no effect on semen parameters. Associated hormonal changes in blood plasma were evaluated.