Pedicle graft epiphysis transplantation

Transfer of a graft taken from the iliac crest apophysis of 48 immature dogs was studied as a means of repairing an epiphysiodesis constituting more than 50% of the growth plate area. Four groups of dogs were studied. In Group I the graft was pedicled on the superficial circumflex iliac vessels and reimplanted in situ. In Group II the pedicled graft was transferred to the groin area as an island graft. These two control groups demonstrate the conservation of growth activity when the graft is pedicled on its epiphyseal vessels. In Group III the graft was transferred to the distal epiphyseal area of the femur after resection of the portion of the growth plate (approximately 2/3) located inside the perichondrial ring, with conservation of 80% of the outer portion of the cylinder. Microsurgical revascularization was achieved by using the saphenous vessels. In Group IV (the control group for Group III) the latter technique was used without revascularization. Roentgenography was performed for nine months after operation. The specimens were studied by tetracycline labeling and histologic and histochemical examinations. Results indicate that a well vascularized graft functions as a dynamic catalyst for regeneration of the resected portion of the growth plate and prevents the formation of bony bridges between the epiphysis and metaphysis by possible activation of the peripheral groove of Ranvier.