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[Does febrile proteinuria exist?].

W H Boesken, A Mamier, H Neumann

    Klinische Wochenschrift
    |September 15, 1983
    PubMed
    Summary
    This summary is machine-generated.

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    Mild proteinuria during fever may be caused by elevated body temperature alone. Significant or persistent proteinuria during infection may indicate underlying kidney disease.

    Area of Science:

    • Nephrology
    • Internal Medicine
    • Pathophysiology

    Context:

    • Proteinuria significance in febrile infectious diseases is underestimated.
    • Distinguishing functional proteinuria from parainfectious nephropathy is crucial.

    Purpose:

    • To investigate the relationship between elevated body temperature and proteinuria.
    • To determine thresholds for proteinuria indicative of kidney disease during febrile illnesses.

    Summary:

    • Experimental hyperthermia in healthy volunteers showed mild proteinuria (<0.65 g/24h) can result from temperature alone.
    • Proteinuria exceeding 0.5-1 g/24h with slow regression suggests glomerular or tubulo-interstitial disease.
    • Transient glomerular alterations were observed, resolving within 12 hours post-hyperthermia.

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    Impact:

    • Highlights the need to consider body temperature when assessing proteinuria in febrile patients.
    • Provides guidance for differentiating fever-induced proteinuria from more serious kidney pathology.
    • Informs clinical evaluation of patients with infectious diseases and urinary protein excretion.