Karyometric changes in the subcommissural organ of male mice after gonadectomy

A karyometric study of the ependymal cells of the subcommissural organ (SCO) was made in male albino mice castrated at 20 days and examined at 25, 35, 45, 55 and 85 days of life, and in control groups of the respective ages. The values of the nuclear areas and perimeters of SCO cells as well as those of the global volume of the SCO are significantly lower in the experimental groups, and the nuclear membrane shows less invaginations. No changes are observed after gonadectomy in the subjacent thalamic ependyma.