Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Mediastinitis after cardiovascular surgery.

D H Bor, R M Rose, J F Modlin

    Reviews of Infectious Diseases
    |September 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Mitochondrial Trifunctional Protein Deficiency: Severe Cardiomyopathy and Cardiac Transplantation.

    JIMD reports·2017
    Same author

    Impact of nurse-delivered community-based CD4 services on facilitating pre-ART care in rural South Africa.

    BMC health services research·2016
    Same author

    A binational registry of adults with pulmonary arterial hypertension complicating congenital heart disease.

    Internal medicine journal·2015
    Same author

    'Cough officer' nurses in a general medical clinic successfully detect drug-susceptible and -resistant tuberculosis.

    Public health action·2014
    Same author

    Mechanical factors in the aetiology of osteoarthrosis.

    Annals of the rheumatic diseases·2014
    Same author

    Religion, Type A behavior, and health.

    Journal of religion and health·2013
    Same journal

    Fatal necrotizing otitis externa in a patient with AIDS.

    Reviews of infectious diseases·1991
    Same journal

    Use of the polymerase chain reaction for the specific and direct detection of Clostridium difficile in human feces.

    Reviews of infectious diseases·1991
    Same journal

    A new case of meningitis due to Pasteurella multocida.

    Reviews of infectious diseases·1991
    Same journal

    Disseminated pelvic actinomycosis presenting as metastatic carcinoma: association with the progestasert intrauterine device.

    Reviews of infectious diseases·1991
    Same journal

    Genetically engineered attenuated herpes simplex viruses.

    Reviews of infectious diseases·1991
    Same journal

    Role of altered drug metabolism in virus-drug interactions.

    Reviews of infectious diseases·1991
    See all related articles

    Postoperative mediastinitis occurred in 3.4% of median sternotomy patients, often linked to serious underlying diseases and reoperation. Early detection and treatment with debridement and antibiotics are crucial, though mortality remains a concern.

    Area of Science:

    • Cardiovascular Surgery
    • Infectious Diseases
    • Surgical Complications

    Background:

    • Postoperative mediastinitis is a serious complication following median sternotomy.
    • Understanding risk factors and clinical presentation is vital for improved patient outcomes.

    Purpose of the Study:

    • To identify host and operative risk factors for mediastinitis after median sternotomy.
    • To characterize the clinical features and microbiology of postoperative mediastinitis.
    • To evaluate treatment strategies and outcomes.

    Main Methods:

    • A case control study analyzing 21 patients with mediastinitis and 42 noninfected controls.
    • Inclusion criteria focused on median sternotomy procedures between 1975 and 1979.
    • Data collected included patient comorbidities, operative details, clinical signs, bacteriology, and outcomes.

    Related Experiment Videos

    Main Results:

    • Mediastinitis complicated 3.4% of median sternotomy procedures.
    • Serious underlying noncardiac diseases (86%) and reoperation (P=.03) were significant risk factors.
    • Gram-negative bacterial infections were associated with earlier onset and higher bacteremia rates (70%).
    • Mortality rate was 24%, with no long-term complications observed in survivors.

    Conclusions:

    • Postoperative mediastinitis is associated with significant patient comorbidities and operative factors.
    • Prompt surgical debridement and appropriate antibiotic therapy are essential for management.
    • While mortality is substantial, survivors experience no long-term sequelae.