Thyroid carcinoma and eosinophilia

An elderly woman with a thyroid nodule slowly growing over ten years is described. During follow-up, this patient developed a rapidly expanding thyroid tumour, multiple lung nodules, hypercalcaemia and pronounced eosinophilia. A needle biopsy of the thyroid revealed a giant-cell carcinoma. This was later confirmed at autopsy. Tumour associated blood eosinophilia has rarely been described with thyroid carcinoma and is discussed here.