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Related Experiment Videos

Plasmapheresis using the IBM 2991 blood cell processor.

D H Buchholz, J R Bove, J R Charette

    Transfusion
    |May 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

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    The IBM 2991 Blood Cell Processor was modified for efficient serial plasmapheresis, enabling plasma harvesting or removal. This adaptable system offers a cost-effective solution for blood cell processing and plasma collection.

    Area of Science:

    • Biomedical Engineering
    • Hematology
    • Medical Devices

    Background:

    • The IBM 2991 Blood Cell Processor is typically used for red blood cell washing and deglycerolization.
    • Plasma collection and therapeutic plasma removal are critical medical procedures.

    Purpose of the Study:

    • To modify the IBM 2991 Blood Cell Processor for serial plasmapheresis.
    • To evaluate the efficiency and cost-effectiveness of the modified system for plasma collection.

    Main Methods:

    • Modification of the IBM 2991 with a roller pump and adapter line.
    • Utilizing the standard disposable processing set for cell washing.
    • Serial withdrawal, centrifugation, plasma removal, and erythrocyte return to the donor.

    Main Results:

    Related Experiment Videos

    • The modified IBM 2991 successfully performed serial plasmapheresis.
    • Multi-unit plasma harvesting or therapeutic removal is feasible.
    • A four-unit plasmapheresis takes 65-75 minutes at a cost of $27.61.

    Conclusions:

    • The modified IBM 2991 is an efficient and cost-effective instrument for plasmapheresis.
    • This modification expands the utility of the IBM 2991 beyond red blood cell processing.
    • The system supports both plasma transfusion and therapeutic plasma exchange.