[The role of serotonin in regulating lipid metabolism in rat liver]

Serotonin is shown to have different effects on the lipid fractions metabolism in the rat liver homogenate and mitochondria depending upon the serotonin concentration. The low serotonin concentration (0.2 mg per 100 g of weight) enhanced lipogenesis in the rat liver; on the contrary, the high serotonin concentration (2 mg per 100 g), as a rule, inhibited this process. It is supposed that the serotonin effect is mediated by the adenyl cyclase system in a cell.