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Updated: May 11, 2026

Reduction in Left Ventricular Wall Stress and Improvement in Function in Failing Hearts using Algisyl-LVR
07:24

Reduction in Left Ventricular Wall Stress and Improvement in Function in Failing Hearts using Algisyl-LVR

Published on: April 8, 2013

Results of surgical therapy in patients with left ventricular aneurysm

J Jehle, M Heerdt, P Spiller

    European Heart Journal
    |September 1, 1983
    PubMed

    Insights

    Surgical intervention for left ventricular aneurysm improved angina and dyspnea in most patients. Aneurysmectomy with or without coronary revascularization reduced aneurysm size and improved heart function, while revascularization alone did not significantly alter these metrics.

    Area of Science:

    • Cardiovascular Surgery
    • Cardiac Surgery Outcomes
    • Left Ventricular Aneurysm Treatment

    Background:

    • Left ventricular aneurysm (LVA) is a serious complication following myocardial infarction.
    • Surgical management of LVA aims to improve clinical outcomes and cardiac function.
    • Optimal surgical strategy for LVA remains a subject of investigation.

    Purpose of the Study:

    • To evaluate the clinical, angiographic, and hemodynamic outcomes of different surgical interventions for LVA.
    • To compare the effectiveness of aneurysmectomy alone, aneurysmectomy with coronary revascularization, and coronary revascularization alone in LVA patients.

    Main Methods:

    • Retrospective analysis of 87 patients with LVA undergoing surgical treatment.
    • Patients were divided into three groups: aneurysmectomy alone (I), aneurysmectomy with coronary revascularization (II), and coronary revascularization alone (III).
    • Clinical symptoms, echocardiographic parameters, and hemodynamic data (including exercise testing) were assessed pre- and postoperatively.

    Main Results:

    • Aneurysm size decreased postoperatively in groups I and II, but not in group III.
    • Angina pectoris improved in patients undergoing revascularization (groups II and III), while aneurysmectomy alone (group I) resulted in no angina in most patients.
    • Left ventricular volumes decreased and ejection fraction increased significantly in groups I and II, but not in group III. Exercise hemodynamics showed reduced pulmonary pressure increase postoperatively in group I.

    Conclusions:

    • Aneurysmectomy, with or without concomitant coronary revascularization, is effective in reducing LVA size and improving left ventricular function.
    • Coronary revascularization alone does not significantly alter LVA size or ventricular function.
    • Surgical intervention for LVA can lead to significant improvements in symptoms and cardiac performance, particularly when addressing the aneurysm itself.

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