Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Haptoglobin typing in Zimbabwe.

M A Raymond, S Fletcher

    Forensic Science International
    |August 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Haptoglobin typing using gradient polyacrylamide gel electrophoresis is effective for differentiating blood phenotypes in Zimbabwe

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Fetal cardiovascular changes during open and fetoscopic in-utero spina bifida closure.

    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2024
    Same author

    FACT effectiveness in primary care; a single visit RCT for depressive symptoms.

    International journal of psychiatry in medicine·2021
    Same author

    Flexible gauge length intrinsic fiber-optic strain sensor using broadband interferometry [Invited].

    Journal of the Optical Society of America. A, Optics, image science, and vision·2020
    Same author

    Peri-operative corticosteroid supplementation for patients on therapeutic glucocorticoids: a national survey.

    Anaesthesia·2020
    Same author

    Guidelines for the management of glucocorticoids during the peri-operative period for patients with adrenal insufficiency: Guidelines from the Association of Anaesthetists, the Royal College of Physicians and the Society for Endocrinology UK.

    Anaesthesia·2020
    Same author

    Using a TRAPS upstream transmission detector to verify multileaf collimator positions during dynamic radiotherapy delivery.

    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2019
    Same journal

    Technical note: Development of a UHPLC-MS/MS method for the analysis of hCG and IGF-I from dried blood spots: A preliminary study.

    Forensic science international·2026
    Same journal

    A novel and robust deep learning model for sibling firearm matching.

    Forensic science international·2026
    Same journal

    Changes in C-reactive protein levels over time in high-temperature environments using postmortem blood.

    Forensic science international·2026
    Same journal

    Insights from the first synthetic cannabinoid clandestine lab dismantled in Brazil.

    Forensic science international·2026
    Same journal

    Determination of the new psychoactive substances MDMB-4en-PINACA, ADB-BUTINACA and some of their metabolites in blood and urine using DLLE-LC-MS/MS: application to real forensic case samples.

    Forensic science international·2026
    Same journal

    The revolver halo as a forensic marker: Raman spectroscopic evidence of primer-driven gunshot residue deposition.

    Forensic science international·2026
    See all related articles

    Area of Science:

    • Biochemistry
    • Genetics
    • Forensic Science

    Background:

    • Haptoglobins are polymorphic proteins involved in hemoglobin binding.
    • Accurate blood typing is crucial for various applications, including forensics and population genetics.
    • Previous methods for haptoglobin typing may have limitations in differentiating certain phenotypes.

    Purpose of the Study:

    • To evaluate the efficacy of haptoglobin typing for characterizing blood in Zimbabwe's negroid population.
    • To assess the utility of gradient polyacrylamide gel electrophoresis for resolving haptoglobin phenotypes.
    • To present data on haptoglobin types in both human and animal populations.

    Main Methods:

    • Gradient polyacrylamide gel electrophoresis (PAGE) was employed for protein separation.

    Related Experiment Videos

  • Analysis was performed on 369 blood samples from individuals of negroid ethnicity.
  • Comparative analysis included both domestic and wild animal blood samples.

    • Main Results:

    • Gradient PAGE demonstrated robust differentiation of haptoglobin phenotypes.
    • All common phenotypes were successfully resolved, including the challenging 2-1M variant.
    • The study provides novel data on haptoglobin allele frequencies in the studied population.

    Conclusions:

    • Haptoglobin typing via gradient PAGE is a reliable and effective method for blood phenotyping in Zimbabwe.
    • This technique offers significant advantages for population genetic studies and forensic investigations.
    • The inclusion of animal data broadens the scope of haptoglobin research in the region.