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Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up
Published on: March 26, 2018
Chest radiographic-pathologic correlation in adult leukemia patients
Investigative Radiology
|November 1, 1983
Summary
Chest radiography in adult leukemia patients frequently reveals abnormalities, with pulmonary infection being the most common cause of opacity. Pneumonia requires prompt consideration in the differential diagnosis due to its prevalence and potential for treatment.
Area of Science:
- Radiology
- Pathology
- Oncology
Background:
- Adult leukemia patients often present with chest complications.
- Radiographic findings can be diverse and challenging to interpret.
Purpose of the Study:
- To correlate radiographic findings with autopsy data in adult leukemia patients.
- To determine the frequency and appearance of leukemic involvement and complications in the chest.
Main Methods:
- Retrospective review of 113 autopsy protocols.
- Radiographic correlation performed on 60 cases.
Main Results:
- Pulmonary infection (67%) was the most common autopsy finding, frequently causing radiographic opacity.
- Leukemic infiltration was present in 26% of cases.
- 90% of chest radiographs showed alveolar or interstitial abnormalities; 40% had pleural effusion.
Conclusions:
- Pulmonary infection is the leading cause of radiographic opacity in adult leukemia patients.
- Pneumonia should be prioritized in the differential diagnosis of chest opacities.
- Early recognition and treatment of pneumonia are crucial due to high mortality and reversibility.
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