Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pulmonary perfusion "without ventilation".

C N Chapman, J J Sziklas, R P Spencer

    Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
    |December 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Sensory and affective dimensions of phasic pain are indistinguishable in the self-report and psychophysiology of normal laboratory subjects.

    The journal of pain·2003
    Same author

    Endodontics: controversial past, exciting present, incredible future.

    The Alpha omegan·2001
    Same author

    Preoperative lymphoscintigraphy during lymphatic mapping for breast cancer: improved sentinel node imaging using subareolar injection of technetium 99m sulfur colloid.

    Journal of the American College of Surgeons·2000
    Same author

    Acquired bile duct blockage: entry of hepatobiliary agent into an intrahepatic abscess.

    Clinical nuclear medicine·2000
    Same author

    Ureteral leak after renal transplantation.

    Clinical nuclear medicine·1999
    Same author

    Persistent and intense activity in multiple loops of small bowel: occurrence in a hepatobiliary examination and a radiogallium study.

    Clinical nuclear medicine·1999
    Same journal

    Overall Survival with [<sup>177</sup>Lu]Lu-PSMA-617 Versus [<sup>177</sup>Lu]Lu-PSMA I&T: A Propensity Score-Matched Real-World Analysis.

    Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
    Same journal

    Toward a Biopsy-Free Diagnosis of Prostate Cancer: Potential of Combined <sup>18</sup>F-Flotufolastat PSMA PET and mpMRI.

    Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
    Same journal

    PSMA PET/CT-Targeted Biopsy in Men with Negative or Equivocal Multiparametric MRI and Exploratory Dynamic Total-Body PET: The FUPERMAN Study.

    Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
    Same journal

    Erratum.

    Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
    Same journal

    Live from 2026 SNMMI Annual Meeting in Los Angeles!

    Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
    Same journal

    CAR T-Cell Therapy for Cancer: Updates and Challenges for Response Assessment.

    Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
    See all related articles

    This case study shows a patient with absent left lung ventilation but continued perfusion on imaging. This "reversed ventilation/perfusion mismatch" highlights factors affecting gas dynamics in diseased lungs.

    Area of Science:

    • Nuclear Medicine
    • Pulmonary Physiology
    • Radiology

    Background:

    • A patient with a history of left upper lobectomy and phrenic nerve injury underwent ventilation/perfusion (V/Q) lung imaging.
    • Previous surgeries and nerve damage can significantly alter lung mechanics and gas exchange.

    Observation:

    • Ventilation imaging revealed no radioactive gas uptake in the left lung during wash-in and equilibrium phases.
    • Perfusion imaging, however, demonstrated continued blood flow to the left lung.
    • Repeat imaging confirmed these findings, with only delayed gas clearance observed during washout.

    Findings:

    • The observed pattern suggests nearly absent ventilation despite preserved perfusion in the left lung.
    • This phenomenon may be attributed to complex factors including post-lobectomy gas dynamics, a bronchial lesion, phrenic nerve damage, and diaphragmatic dysfunction.

    Related Experiment Videos

    Implications:

    • This case underscores the importance of assessing the degree of ventilation and inter-pulmonary phase relationships in V/Q imaging.
    • It raises questions about the threshold of ventilation required for accurate radioactive gas entry into compromised lung segments.
    • The findings highlight the potential for "reversed ventilation/perfusion mismatch" in complex pulmonary conditions.