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[Multiple meningioma]
Abstract:
Meningiomas are the most popular benign intracranial tumors, but they are rarely seen as a multiple growth. The incidence of multiple meningiomas, defined by Cushing and Eisenhardt, is about 1 to 2 per cent of all meningioma cases. Though many cases of the multiple meningiomas were reported previously in the world, some of them were concomitant with von Recklinghausen's disease or acoustic neurinoma. Most of the cases of the multiple meningiomas reported showed multiple lesion at the time of operation or after a few years of the initial operation. We have encountered two patients with multiple meningioma without the stigmata of von Recklinghausen's disease in our clinic. Case 1. A 58-year-old female visited the hospital complaining of headache and occasional nausea on February 6, 1980. Plain and enhanced cT confirmed a large tumor in the right parietal region and three small tumor nodules in the right occipital region. Carotid angiogram detected only two tumors of frontal falx. Apparent two tumor stains were seen on the region, and they were fed by meningeal frontal and parietal region, and they were fed by meningeal arteries through the right ophthalmic artery. A large tumor of parietal and a small tumor of frontal region on the right side of falx were removed. Three nodular tumors of right occipital convexity were extirpated at the same time. Histological examination of the tumors disclosed all extirpated tumors were fibroblastic meningioma. Case 2. A 61-year-old male developed convulsive seizure of the right upper limb and right side of the face was diagnosed as having convexity meningioma in the left parietal region.(ABSTRACT TRUNCATED AT 250 WORDS)
Insights
Multiple meningiomas are rare benign brain tumors. This study presents two cases of multiple meningiomas without associated neurofibromatosis, highlighting their occurrence and surgical management.
Area of Science:
- Neurosurgery
- Oncology
- Neuropathology
Background:
- Meningiomas are common benign intracranial tumors, typically solitary.
- Multiple meningiomas are rare, occurring in 1-2% of cases.
- Previous reports often link multiple meningiomas to neurofibromatosis or acoustic neurinoma.
Observation:
- Two patients with multiple meningiomas, lacking stigmata of von Recklinghausen's disease, were treated.
- Case 1: A 58-year-old female with a large right parietal tumor and three occipital nodules.
- Case 2: A 61-year-old male with a left parietal convexity meningioma.
Findings:
- Histological examination confirmed all tumors in Case 1 were fibroblastic meningiomas.
- Imaging revealed multiple lesions in both patients, with some feeding arteries identified via angiography.
- Both patients underwent surgical resection of their multiple meningiomas.
Implications:
- These cases expand the understanding of multiple meningiomas presentation.
- Highlights the possibility of multiple meningiomas occurring independently of genetic syndromes.
- Underscores the importance of thorough evaluation for multiple lesions even without typical associated conditions.