Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Marfan's syndrome].

M Martelli, A Saponaro

    Minerva Medica
    |October 27, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Marfan disease is a genetic disorder affecting connective tissue, leading to skeletal, ocular, cardiac, and respiratory issues. Diagnosis relies on recognizing typical lesions due to unknown biochemical errors.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Metabolic heterogeneity-based radiomic model predicts treatment outcomes of primary mediastinal B-cell lymphoma patients in the IELSG37 study.

    British journal of haematology·2026
    Same author

    Correction: Siltuximab as a first-line therapy for idiopathic multicentric Castleman disease: a retrospective analysis based on the SiMuLa study of the Italian regional network.

    Frontiers in oncology·2026
    Same author

    Oral hygiene management in critically ill patients: prevention of ventilator-associated pneumonia.

    Frontiers in dental medicine·2026
    Same author

    Siltuximab as a first-line therapy for idiopathic multicentric Castleman disease: a retrospective analysis based on the SiMuLa study of the Italian regional network.

    Frontiers in oncology·2026
    Same author

    Corrigendum to "First-line therapy with daratumumab, lenalidomide and dexamethasone for patient with POEMS syndrome: A case report" [Leukemia Research Reports (2024) Volume 22, 100491].

    Leukemia research reports·2025
    Same author

    Baseline, Drug-Related and Persistent Anemia and/or Thrombocytopenia Predict Responses and Prognosis in Myelofibrosis Patients Treated With Ruxolitinib.

    Hematological oncology·2025
    Same journal

    How to become a centenarian in four weeks?. Myths and limits of longevity recipes: a critical review.

    Minerva medica·2026
    Same journal

    Comparative efficacy and safety between intravenous recombinant human prourokinase and alteplase in acute ischemic stroke treatment: a meta-analysis of randomized controlled trials.

    Minerva medica·2026
    Same journal

    Efficacy and safety of oral tapentadol for cancer-related pain: an updated systematic review and meta-analysis.

    Minerva medica·2026
    Same journal

    Use of the neurostimulator in thyroidectomy procedures: comparison between vagal and recurrent laryngeal nerve stimulation.

    Minerva medica·2026
    Same journal

    Iron deficiency and risk of acute kidney injury after TAVI: a machine learning analysis.

    Minerva medica·2026
    Same journal

    Therapeutic adherence and health literacy: a perfect match in dyslipidemic patients.

    Minerva medica·2026
    See all related articles

    Area of Science:

    • Genetics and Molecular Biology
    • Cardiology
    • Pulmonology

    Context:

    • Marfan disease is a hereditary connective tissue disorder.
    • It results from a congenital disorder of fibrous support proteins like collagen and elastin.
    • Sporadic forms with uncertain interpretation also exist.

    Purpose:

    • To discuss the diagnosis and management of Marfan disease.
    • To highlight the importance of recognizing systemic and less common manifestations.
    • To review current therapeutic approaches.

    Summary:

    • Marfan disease presents with diverse skeletal, ocular, cardiac, and respiratory alterations.
    • Diagnosis is clinical, based on characteristic lesions, as biochemical tests are lacking.
    • Advanced cardiac assessment may reveal reduced ventricular compliance and myocardial fibrosis.

    Related Experiment Videos

  • Prognosis is influenced by the extent of organ damage, particularly cardiac involvement.

    • Impact:

    • Emphasizes the need for thorough clinical examination to detect all affected systems.
    • Underscores the significance of cardiac and respiratory involvement in prognosis.
    • Provides an overview of current management strategies for Marfan disease.