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Related Experiment Videos

[Corynebacterium acnes osteitis. A case in a child].

J J Louis, J Berard, X Cottin

    Pediatrie
    |July 1, 1983
    PubMed
    Summary

    A rare case of Corynebacterium acnes osteitis in an 11-year-old girl mimicked cancer radiologically. Prompt treatment with Pristinamycin led to a complete cure, highlighting effective therapeutic outcomes.

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    Area of Science:

    • Pediatric Osteomyelitis
    • Infectious Diseases
    • Radiology and Pathology

    Background:

    • Osteitis, an inflammation of bone, can be caused by various pathogens.
    • Corynebacterium acnes (now Cutibacterium acnes) osteitis is an uncommon but significant diagnosis in pediatric cases.
    • Distinguishing infectious osteitis from malignant bone tumors is crucial for appropriate management.

    Observation:

    • An 11-year-old female presented with a lesion in the upper right tibia.
    • Radiological imaging suggested a malignant bone tumor.
    • Histological examination revealed features consistent with tuberculosis, adding diagnostic complexity.
    • Scintigraphy indicated secondary involvement of the seventh right rib.

    Findings:

    • The causative agent was identified as Corynebacterium acnes.
    • The osteitis presented with atypical radiological and histological features.
    • Successful treatment was achieved with Pristinamycin over a 3-month period.

    Implications:

    • This case underscores the importance of considering infectious etiologies, even with concerning radiological and histological findings.
    • Early and accurate diagnosis of pediatric osteitis is vital for preventing long-term morbidity.
    • Pristinamycin demonstrates efficacy in treating refractory or complex cases of Corynebacterium acnes osteitis.

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