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Updated: Aug 11, 2026

Isolation, Fixation, and Immunofluorescence Imaging of Mouse Adrenal Glands
Published on: October 2, 2018
[Androgenic function of the adrenal cortex in girl athletes with retarded sexual development]
Abstract:
Diurnal excretion of 17-ketosteroids and their fractions was studied in 43 girl athletes with retarded sexual development (RSD) and 22 patients who did not go in for sports. Twenty-five healthy girls with a normal menstrual cycle constituted the control group. Athletes with RSD showed relative hyperandrogeny marked by a higher proportion of more active androgenic fractions (dehydroepiandrosterone and androsterone) in total 17-ketosteroids. Excretion of neutral 17-ketosteroids in athletes examined, as compared with non-athletes with RSD, was within age-associated norms or surpassed them. It is suggested that androgens of the adrenal cortex are involved into the pathogenesis of RSD in female athletes.
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