Glutamic-oxalacetic transaminase (SGOT) and glutamic-pyruvic transaminase (SGPT) in newborns in relation to the...

The transaminase enzymatic activity (SGOT-SGPT) was measured in the first 72h. of life, within the 7th day and on the 30th day of life in two groups of new borns i.e. full-term and premature ones with a gestational age less than or equal to 37 weeks. The premature babies were divided into two sub-groups: babies with a gestational ager less than or equal to 32 and greater than 32 weeks. Our results on the SGOT and SGPT activity in healthy full-term newborns agree with literature data, but indicate a lowering of the SGOT mean values at the 30th day of life. A similar lowering occurs at the 7th day of life; in premature newborns; these have lower SGOT values during the first 72h. of life than full-term newborns. Newborns with a gestational age of less than or equal to 32 weeks have higher SGOT values than newborns with a gestational age of greater than 32 weeks. The mean values of SGPT during the first days of life are higher in full-term than in premature newborns; there are no significant differences in the sub groups with different gestational age.