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Primary granulomatous dermatitis caused by Rhodochrous. Evidence for a pathogenic role in humans
Archives of Dermatology
|December 1, 1983
Summary
Rhodochrous bacteria, rarely causing human infections, were identified in a patient with a skin granuloma. Successful treatment with doxycycline hydrochloride suggests its efficacy for Rhodochrous cutaneous infections.
Area of Science:
- Microbiology
- Dermatology
- Infectious Diseases
Background:
- The taxonomic status of bacteria within the Rhodochrous complex is uncertain, with these organisms being more closely related to Nocardia than Mycobacterium.
- Organisms from the Rhodochrous complex are infrequently associated with human pathogenicity.
Observation:
- An 81-year-old male presented with a plaquelike cutaneous granuloma.
- Rhodochrous bacteria were successfully cultured from the patient's skin lesion.
- The presence of Rhodochrous was confirmed in tissue sections of the granuloma.
Findings:
- This case suggests a pathogenic role for Rhodochrous in causing primary cutaneous infections.
- Specific antimicrobial therapy using doxycycline hydrochloride was administered.
- The patient experienced a successful treatment outcome with no recurrence of infection for three years.
Implications:
- This study highlights Rhodochrous as a potential cause of cutaneous granulomas.
- Doxycycline hydrochloride may be an effective treatment for Rhodochrous-induced skin infections.
- Further research into the pathogenicity and treatment of Rhodochrous complex infections is warranted.