Related Experiment Video
Updated: Aug 12, 2026

An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)
Published on: January 27, 2010
Extradural morphine for the relief of pain following caesarean section
Abstract:
Thirty patients took part in a double-blind trial to compare morphine 10 mg i.m. with morphine 5 mg into the extradural space for pain relief following Caesarean section. With the extradural route the mean time to first analgesia was 7.95 h compared with 4.75 h for the i.m. route. The mean number of further doses of diamorphine 7.5 mg required for pain relief in the first 24 h was 1.93 (+/- 0.30) in the i.m. group and 1.46 (+/- 0.31) in the extradural group. There was a small but definite advantage in the use of the extradural route for the initial dose of morphine. No serious side-effects were noted in either group.
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