[Water distribution around a protein molecule from data on spatial structure]
Related Experiment Video
Updated: Aug 12, 2026
09:51
Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
Published on: July 16, 2017
Biofizika
|November 1, 1983
Abstract:
Water distribution was calculated using the structure data of protein rubredoxin (K. Watenlaugh et al. J. Mol. Biol., 138, 615, 1980). By this method the hydration surrounding of macromolecules was localized in the spheres of the 3,2 A radius with the error 8%. A detailed analysis of the data on water localization in the protein crystal shows that hydration water distribution consists of the associates of water molecules and does not form the "hydration shell".
More Related Videos
Related Concept Videos
01:13Protein Organization
Overview
01:22Protein Folding
Overview
01:13Protein Organization
Overview
01:24Protein Diffusion in the Membrane
Proteins show rotational as well as lateral diffusion across the membrane. The lateral diffusion of proteins was confirmed through the cell fusion experiment where mouse and human cells were fused, resulting in hybrid cells. When the human and mouse cells fused, the specific membrane proteins on human and mouse cells were marked with the red and green-fluorescent markers, respectively. Initially, the red and green fluorescence was located on the respective hemisphere of the cell. As time...
01:25Aquaporins
Aquaporins or AQPs are a family of integral membrane proteins whose primary function is to transport water, while some called aquaglyceroporins also transport glycerol. In addition, aquaporins have also been suspected to be involved in transporting volatile substances, such as carbon dioxide and ammonia, across membranes. Such AQPs that act as gas channels are often highly expressed in cells involved in the gaseous exchange, such as red blood cells, epithelial cells, and pulmonary capillaries.
01:24Protein Organization
Proteins are polymers of amino acid residues. They are versatile and responsible for different cellular functions, including DNA replication, molecular transport, catalysis, and structural support. Proteins have a hierarchical structure comprising at least three levels of organization: primary, secondary, and tertiary structure. Some large proteins have a quaternary structure where individual protein subunits are linked together.
The primary structure of a protein is its amino acid sequence.
The primary structure of a protein is its amino acid sequence.