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[Analysis of the hemodynamic effects of fentanyl in waking cats]
Abstract:
It has been shown in experiments on conscious cats with the aid of multifactorial analysis that the main effects of phentanyl given in doses of 15 and 30 micrograms/kg on the systemic hemodynamics proved to be hypertensive and tachycardic. One of the mechanisms of the chronotropic effect of the drug was partially realized through the inhibition of the baroreceptor reflex. The individual characteristics of the hemodynamic effect of the analgetic depended on the animals' initial status and might be predicted thereby.