[Chromosomal analysis of primary superficial tumors of the bladder]

Cytogenetic analysis of resected bladder tumors was performed in 32 patients. None of these patients had previous irradiation or chemotherapy. Direct chromosome preparations were made. Of the 32 preparations, 22 had chromosome abnormalities. We have observed a good correlation between the chromosome abnormalities and the Stage/Grade of the tumors. Patients were followed from 6 to 33 months. During this period, 82% of the patients with noninvasive or submucosal invasive bladder tumors and chromosome abnormalities have had recurrences. The existence of a good correlation between chromosomal abnormalities and the capacity of the neoplasm to recur was confirmed.