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[Pathomorphology of lymphoid tissue at late periods after anaphylactic shock]
Abstract:
The lymph nodes (mesenteric, popliteal) and the thymus of rabbits were examined pathomorphologically and morphometrically in short-term (2-3 days) and long-term (8-10 days) periods after anaphylactic shock (AS). The main alteration that developed in the lymph nodes after AS was a decrease in the size of the follicles with the manifestations of depletion. Along with multiple mitoses in reticular and blast cells the follicles of the lymph nodes demonstrated a considerable lessening in the lymphocyte count and alterations - pyknosis, rhexis, lysis of their nuclei with phagocytosis of the fragments by reticular cells. The presence of destructive alterations in lymphoid tissue seen in the long-term periods after AS points to the delayed recovery of the morphological integrity of lymphoid tissue as compared with the clinical convalescence.