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Congenital measles--1982.

B Muhlbauer, L M Berns, A Singer

    Israel Journal of Medical Sciences
    |November 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Perinatal measles can cause illness in newborns, but prompt treatment with human serum globulin may lead to good outcomes. This study reports two cases of infants born with measles during an epidemic.

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    Area of Science:

    • Pediatrics
    • Infectious Diseases
    • Virology

    Background:

    • Congenital measles, acquired in utero, presents a wide spectrum of clinical severity.
    • The 1982 measles epidemic provided an opportunity to study perinatal measles cases.

    Observation:

    • Two infants born during the 1982 measles epidemic were identified with perinatal measles.
    • Mothers presented with fever and rash shortly before delivery.
    • Infants initially appeared normal but developed hyperbilirubinemia, with one requiring exchange transfusion.

    Findings:

    • One infant developed a delayed maculopapular rash without constitutional symptoms.
    • Viral cultures from infants were negative.
    • Serological tests confirmed measles infection with rising hemagglutination inhibition antibody titers.

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    Implications:

    • Human serum globulin administration appears to be a safe and potentially effective treatment for perinatal measles.
    • Early diagnosis and intervention are crucial for managing congenital measles.
    • Further research is needed to fully understand the long-term effects and optimal management strategies for perinatal measles.