Related Experiment Video
Updated: Aug 14, 2026

Determining the Phagocytic Activity of Clinical Antibody Samples
Published on: November 30, 2011
[Immunoglobulins in man. Biological properties and therapeutic aspects]
Abstract:
The therapy with (modified) immune serum globulin implies critical limitation of therapeutic indications as well as the knowledge of the biological and physical properties of the immunoglobulin preparations. While the therapeutic effect in prophylaxis and substitution therapy is well established, the benefit has still to be proven for the therapy of severe acute infections. The predominant role of antibodies in the defense against bacterial and some viral infections encourages for the use of immune serum globulin in acute infections.
Related Concept Videos
Humoral Immune Responses
Antibody Structure
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
Antibody Structure
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
Transcytosis of IgG
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
Antibody Structure and Classes
The basic structure of an antibody consists of four protein chains: two identical heavy chains and two identical light chains. These chains are held together by disulfide bonds and other non-covalent interactions, forming a Y-shaped structure.
Antibody Actions
Neutralization
Antibodies can bind to pathogens, preventing them from infecting host cells. This process...

