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Side effects of timolol
Survey of Ophthalmology
|December 1, 1983
Abstract:
Timolol maleate, a nonselective beta blocker, has been associated with adverse reactions when administered topically or systemically. The current literature pertaining to timolol-related side effects and reports to the National Registry of Drug Induced Ocular Side Effects are reviewed. Knowing what side effects are associated with the systemic administration of timolol is helpful in predicting systemic side effects that may be encountered when timolol is administered topically.
Insights
Timolol maleate, a nonselective beta blocker, can cause adverse reactions. Reviewing systemic side effects helps predict potential issues from topical timolol use.
Area of Science:
- Ophthalmology
- Pharmacology
Background:
- Timolol maleate is a nonselective beta-blocker used in treating conditions like glaucoma.
- Both topical and systemic administration of timolol maleate have been linked to adverse reactions.
Purpose of the Study:
- To review existing literature on timolol maleate side effects.
- To analyze reports from the National Registry of Drug Induced Ocular Side Effects.
- To establish a correlation between systemic and topical timolol administration side effects.
Main Methods:
- Literature review of studies on timolol maleate adverse reactions.
- Analysis of case reports submitted to the National Registry of Drug Induced Ocular Side Effects.
Main Results:
- Timolol maleate is associated with various adverse reactions.
- Systemic administration of timolol maleate can lead to specific side effects.
- Topical administration may also result in systemic absorption and subsequent side effects.
Conclusions:
- Understanding systemic side effects of timolol maleate is crucial.
- This knowledge aids in anticipating and managing potential adverse events from topical timolol application.
- Ocular side effects from topical timolol can mirror systemic effects.