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Updated: Aug 11, 2026

A Low Mortality Rat Model to Assess Delayed Cerebral Vasospasm After Experimental Subarachnoid Hemorrhage
Published on: January 17, 2013
[New method for the experimental production of subarachnoid hemorrhage]
Abstract:
A new method for an experimental subarachnoid hemorrhage in a cat is described. It attempts to simulate closely a bleeding from a ruptured aneurysm. An approach through the mouth and presphenoid sinus offers to the internal carotid, cerebral anterior, media and anterior communicating arteries. Needle puncture produces local stress to the artery characteristic for aneurysm rupture. The bleeding occurs to the subarachnoid in a closed skull, since the bone opening untouched by the preparation. The method has been compared with other procedures for experimental subarachnoidal hemorrhage. The method is applicable to experimental studies on pathophysiological, metabolic and, vascular changes, after subarachnoid hemorrhage.

