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Updated: Aug 8, 2026

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Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis
Published on: December 18, 2010
[Anesthesia and intensive therapy in acute suppurative peritonitis]
Vestnik Khirurgii Imeni I. I. Grekova
|December 1, 1983
Summary
Programmed intravenous narcosis with Darenthin improved hemodynamic indices and oxygenation in acute purulent peritonitis patients. This therapy accelerated intestinal peristalsis and portal blood flow, aiding recovery.
Area of Science:
- Medical Science
- Anesthesiology
- Critical Care Medicine
Context:
- Acute purulent peritonitis presents significant challenges in hemodynamic management and gastrointestinal recovery.
- Optimizing oxygenation and circulatory function is crucial for patient outcomes in severe abdominal sepsis.
Purpose:
- To evaluate the effects of programmed intravenous narcosis combined with Darenthin on hemodynamic parameters and oxygen regimen in patients with acute purulent peritonitis.
- To assess the impact of Darenthin on portal blood flow and the restoration of intestinal peristalsis.
Summary:
- The study involved 58 patients diagnosed with acute purulent peritonitis.
- Administration of programmed intravenous narcosis alongside Darenthin led to significant increases in cardiac index and stroke index.
- Darenthin, as part of intensive therapy, enhanced portal blood flow and promoted earlier recovery of intestinal motility.
Impact:
- The findings suggest that Darenthin can be a valuable adjunct in managing hemodynamics and accelerating gastrointestinal function in peritonitis.
- This therapeutic approach may improve patient recovery trajectories and reduce complications associated with prolonged ileus.
- Further research could explore optimal Darenthin dosing and its long-term effects in critical surgical conditions.
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