[Determination of N-acetyl-glucosaminidase (NAG) in diabetic subjects]

NAG activity was measured in the serum of 40 diabetic subjects and 38 normal subjects. Diabetic subjects were divided into 8 groups on the ground of diabetic pattern, therapy and complications. Results showed significantly higher NAG activity in diabetics in comparison with normals. Inside the 8 groups of diabetic subjects, correlation between serum NAG activity and Hg A1 concentration appeared significant (P less than 0.001). Therefore NAG activity in diabetics appears rather related to the degree of glycometabolic control than to the presence of diabetes complications.