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Related Experiment Videos

[Total cystectomy for bladder tumor: eight-year experience].

Y Arai, T Taniguchi, S Kaku

    Hinyokika Kiyo. Acta Urologica Japonica
    |November 1, 1983
    PubMed
    Summary

    This study on total cystectomy and urinary diversion found survival rates dependent on tumor stage and grade. Patient age did not significantly impact survival outcomes.

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    Rac regulates vascular endothelial growth factor stimulated motility.

    Cell communication & adhesion·2002

    Area of Science:

    • Urology
    • Oncology

    Context:

    • Retrospective analysis of 39 patients undergoing total cystectomy and urinary diversion between 1975 and 1982.
    • Evaluated outcomes of ileal conduit and ureterocutaneostomy diversions, with 10 patients receiving preoperative irradiation.

    Purpose:

    • To assess the outcomes, complications, and survival rates following total cystectomy and urinary diversion.
    • To determine the influence of tumor stage, grade, and patient age on survival.

    Summary:

    • Postoperative mortality was 2.6%, with early complications in 38.5% (e.g., wound infection, pyelonephritis, obstruction).
    • Late complications included ureteroileal stricture. Overall 1-, 3-, and 5-year survival rates were 92.4%, 56.6%, and 41.7%, respectively.
    • Survival was significantly correlated with tumor stage and grade, but not patient age (>=65 vs. <65 years).

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    Impact:

    • Provides long-term survival data for cystectomy and urinary diversion procedures.
    • Highlights the importance of tumor characteristics in predicting patient outcomes.
    • Informs clinical decision-making regarding patient selection and treatment strategies for bladder cancer.