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Related Experiment Videos

[A case of true hermaphroditism].

H Fuse, H Minagawa, H Ito

    Hinyokika Kiyo. Acta Urologica Japonica
    |April 1, 1983
    PubMed
    Summary

    A 2-year-old female with ambiguous genitalia was diagnosed with ovotestis. Surgical intervention aimed to feminize characteristics, confirming the histological diagnosis of ovotestis.

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    Area of Science:

    • Endocrinology
    • Genetics
    • Pediatric Surgery

    Background:

    • Ambiguous genitalia in pediatric patients presents diagnostic and management challenges.
    • Disorders of sex development (DSD) require a multidisciplinary approach for accurate diagnosis and treatment.
    • This case highlights a rare presentation of DSD in a young child.

    Observation:

    • A two-year-old child presented with ambiguous genitalia, including a hypertrophied clitoris and palpable testis-like mass.
    • Karyotype revealed 46XX, with normal urinary and serum hormone levels.
    • Vaginography and exploratory laparotomy confirmed the presence of a uterus, fallopian tube, and bilateral gonads (ovotestes).

    Findings:

    • Histological examination confirmed both gonads as ovotestis.
    • Surgical management included clitoroplasty, removal of the right gonad, and resection of the testicular portion of the left gonad.
    • The ovarian portion of the left gonad was biopsied for further analysis.

    Implications:

    • This case underscores the importance of thorough investigation in pediatric ambiguous genitalia.
    • Accurate histological diagnosis of ovotestis is crucial for appropriate surgical and long-term management.
    • Understanding the spectrum of DSD aids in optimizing patient care and outcomes.

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